The role of bacterial metabolism in antimicrobial resistance

This Review discusses the complex relationship between bacterial metabolism and antibiotic treatment, highlighting how metabolism impacts antibiotic efficacy, antimicrobial resistance (AMR) evolution, and mechanisms. It highlights the importance of understanding these relationships for improving public and human health. The review highlights the role of metabolism in clinical contexts and explores the future of metabolic-based strategies for personalized antimicrobial therapies. A deeper understanding is crucial for addressing AMR and developing effective therapeutics.